• Symptoms of End-stage Renal Disease (ESRD)

    The Kidney and Its Main Blood Vessels
    Copyright © Nucleus Medical Media, Inc.
    As kidney failure progresses, some of the following symptoms may develop:
    • Loss of appetite
    • Nausea and vomiting
    • Fatigue
    • Weight loss
    • Itchy skin
    • Confusion
    • Trouble concentrating
    • Swelling throughout the body
    • Low urine output
    • Generalized weakness
    • Multiple bruises
    • Numbness and tingling in the extremities
    • Irritability
    • Decreased desire for sexual activity
    • Menstrual irregularities
    • Constipation
    • Diarrhea
    • Muscle cramps and twitches
    • Shortness of breath
    • Chest pain
    • Weak, brittle bones
    • Yellowish-brownish skin tone
    • Headache
    • Frequent hiccups
    If kidney failure is untreated, the waste products and fluid that build up can result in:
    • Coma
    • Seizures
    • Death


    Chronic kidney disease. EBSCO DynaMed website. Available at: http://www.ebscohost.com/dynamed . Updated April 22, 2013. Accessed July 2, 2013.

    End-stage renal disease. National Institute of Diabetes & Digestive & Kidney Diseases website. Available at: http://www2.niddk.nih.gov/Research/ScientificAreas/Kidney/KEB.htm Updated September 15, 2010. Accessed July 2, 2013.

    Yu, HT. Progression of chronic renal failure. Arch Int Med . 2003;163:1417-1429.

    Revision Information

  • LiveWell personal health survey

    How healthy are you really? Find out – free.Learn more

    It's time to stop guessing. If you want to make some changes but just aren't sure how, the free personal health survey from LiveWell is a great place to start.

  • HeartSHAPE Spotlight

    At risk for a heart attack? Learn more

    Fight heart disease and prevent heart attacks. HeartSHAPE® is a painless, non-invasive test that checks pictures of your heart for early-stage coronary disease.

  • Calories and Energy Needs

    Calorie NeedsLearn more

    How many calories do you need to eat each day to maintain your weight and fuel your physical activity? Enter a few of your stats into this calculator to find out.

  • Ideal Body Weight

    Ideal Body WeightLearn more

    Using body mass index as a reference, this calculator determines your ideal body weight range. All you need to do is enter your height.

  • Body Mass Index

    Body Mass IndexLearn more

    This tool considers your height and weight to assess your weight status.

  • Can we help answer your questions?

    Wellmont Nurse Connection is your resource for valuable health information any time, 24 hours a day, seven days a week. Speak to a Nurse any time, day or night, at (423) 723-6877 or toll-free at 1-877-230-NURSE.