2011501342 Health Library | Health and Wellness | Wellmont Health System
  • Acetaminophen and Codeine

    (a set a mee' noe fen) (koe' deen)

    WHY is this medicine prescribed?

    This combination of drugs is used to relieve mild to moderate pain.
    This medication is sometimes prescribed for other uses; ask your doctor or pharmacist for more information.

    HOW should this medicine be used?

    The combination of acetaminophen and codeine comes as a tablet, capsule, and liquid to take by mouth. It usually is taken every 6 hours as needed. Follow the directions on your prescription label carefully, and ask your doctor or pharmacist to explain any part you do not understand. Take acetaminophen and codeine exactly as directed.
    Codeine can be habit-forming. Do not take a larger dose, take it more often, or for a longer period than your doctor tells you to.

    What SPECIAL PRECAUTIONS should I follow?

    Before taking acetaminophen and codeine,
    • tell your doctor and pharmacist if you are allergic to acetaminophen, codeine, sulfite or any other drugs.
    • tell your doctor and pharmacist what prescription and nonprescription medications you are taking, especially acetaminophen (Tylenol); antidepressants; medications for cough, cold, or allergies; other pain relievers; sedatives, sleeping pills, tranquilizers; and vitamins.
    • tell your doctor if you have or have ever had liver or kidney disease, a history of alcoholism, lung or thyroid disease, prostatic hypertrophy, or urinary retention.
    • tell your doctor if you are pregnant, plan to become pregnant, or are breast-feeding. If you become pregnant while taking acetaminophen and codeine, call your doctor.
    • if you are having surgery, including dental surgery, tell the doctor or dentist that you are taking acetaminophen and codeine.
    • you should know that this drug may make you drowsy. Do not drive a car or operate machinery until you know how this drug affects you.
    • remember that alcohol can add to the drowsiness caused by this drug.

    What should I do IF I FORGET to take a dose?

    This medication usually is taken as needed. If your doctor has told you to take acetaminophen and codeine regularly, take the missed dose as soon as you remember it. However, if it is almost time for the next dose, skip the missed dose and continue your regular dosing schedule. Do not take a double dose to make up for a missed one.

    What SIDE EFFECTS can this medicine cause?

    Acetaminophen and codeine may cause side effects. Tell your doctor if any of these symptoms are severe or do not go away:
    • dizziness
    • lightheadedness
    • drowsiness
    • upset stomach
    • vomiting
    • constipation
    • stomach pain
    • rash
    • difficulty urinating
    If you experience either of the following symptoms, call your doctor immediately:
    • difficulty breathing
    • mood changes
    If you experience a serious side effect, you or your doctor may send a report to the Food and Drug Administration's (FDA) MedWatch Adverse Event Reporting program online [at http://www.fda.gov/Safety/MedWatch ] or by phone [1-800-332-1088].

    What should I know about STORAGE and DISPOSAL of this medication?

    Keep this medication in the container it came in, tightly closed, and out of reach of children. Store it at room temperature and away from excess heat and moisture (not in the bathroom). Throw away any medication that is outdated or no longer needed. Talk to your pharmacist about the proper disposal of your medication.

    What should I do in case of OVERDOSE?

    In case of overdose, call your local poison control center at 1-800-222-1222. If the victim has collapsed or is not breathing, call local emergency services at 911.

    What OTHER INFORMATION should I know?

    Keep all appointments with your doctor.
    Too much acetaminophen may cause liver damage; do not take more than 4000 mg of acetaminophen per day.
    Do not let anyone else take your medication. Ask your pharmacist any questions you have about refilling your prescription.
    It is important for you to keep a written list of all of the prescription and nonprescription (over-the-counter) medicines you are taking, as well as any products such as vitamins, minerals, or other dietary supplements. You should bring this list with you each time you visit a doctor or if you are admitted to a hospital. It is also important information to carry with you in case of emergencies.

    Brand Names

    • Capital® & Codeine (as a combination product containing Acetaminophen, Codeine)
    • Cocet® (as a combination product containing Acetaminophen, Codeine)
    • Codrix® (as a combination product containing Acetaminophen, Codeine)
    • Colrex® (as a combination product containing Acetaminophen, Chlorpheniramine, Codeine, Phenylephrine)
    • Combiflex® ES (as a combination product containing Acetaminophen, Codeine, Magnesium Salicylate, Phenyltoloxamine)
    • Cotabflu® (as a combination product containing Acetaminophen, Chlorpheniramine, Codeine)
    • Fioricet® with Codeine (as a combination product containing Acetaminophen, Butalbital, Caffeine, Codeine)
    • Margesic® #3 (as a combination product containing Acetaminophen, Codeine)
    • Maxiflu® (as a combination product containing Acetaminophen, Codeine, Guaifenesin, Pseudoephedrine)
    • Phenaphen® with Codeine (#3, #4) (as a combination product containing Acetaminophen, Codeine)
    • Phenco-Care® (as a combination product containing Acetaminophen, Codeine)
    • Phenflu® (as a combination product containing Acetaminophen, Codeine, Guaifenesin, Phenylephrine)
    • Phrenilin® with Caffeine, Codeine (as a combination product containing Acetaminophen, Butalbital, Caffeine, Codeine)
    • Pyregesic® (as a combination product containing Acetaminophen, Codeine)
    • Tylagesic® (as a combination product containing Acetaminophen, Codeine)
    • Tylenol® with Codeine (#2, #3, #4) (as a combination product containing Acetaminophen, Codeine)
    • Vopac® (as a combination product containing Acetaminophen, Codeine)

    Other Names

    • APAP and Codeine (as a combination product containing Acetaminophen and Codeine)
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