• Penicillin G Potassium or Sodium Injection

    (pen i sill' in)

    WHY is this medicine prescribed?

    Your doctor has ordered penicillin, an antibiotic, to help treat your infection. The drug will be either injected into a large muscle (such as your buttock or hip) or added to an intravenous fluid that will drip through a needle or catheter placed in your vein for 30 minutes or more, four to six times a day.
    Penicillin eliminates bacteria that cause many kinds of infections, including pneumonia; meningitis; and skin, bone, joint, stomach, blood, and heart valve infections. This medication is sometimes prescribed for other uses; ask your doctor or pharmacist for more information.
    Your health care provider (doctor, nurse, or pharmacist) may measure the effectiveness and side effects of your treatment using laboratory tests and physical examinations. It is important to keep all appointments with your doctor and the laboratory. The length of treatment depends on how your infection and symptoms respond to the medication.

    What SPECIAL PRECAUTIONS should I follow?

    Before administering penicillin,
    • tell your doctor and pharmacist if you are allergic to penicillin, cephalosporins [e.g., cefaclor (Ceclor), cefadroxil (Duricef), or cephalexin (Keflex)], or any other drugs.
    • tell your doctor and pharmacist what prescription and nonprescription medications you are taking, especially other antibiotics, anticoagulants ('blood thinners') such as warfarin (Coumadin), aspirin or other nonsteroidal anti-inflammatory medications such as naproxen (Anaprox) or ibuprofen (Motrin), atenolol (Tenormin), diuretics ('water pills'), oral contraceptives, probenecid (Benemid), and vitamins.
    • tell your doctor if you have or have ever had kidney or liver disease, allergies, asthma, blood disease, colitis, stomach problems, or hay fever.
    • tell your doctor if you are pregnant, plan to become pregnant, or are breast-feeding. If you become pregnant while taking penicillin, call your doctor.
    • if you have diabetes and regularly check your urine for sugar, use Clinistix or TesTape. Do not use Clinitest tablets because penicillin may cause false positive results.

    HOW should this medicine be used?

    Before you administer penicillin, look at the solution closely. It should be clear and free of floating material. Gently squeeze the bag or observe the solution container to make sure there are no leaks. Do not use the solution if it is discolored, if it contains particles, or if the bag or container leaks. Use a new solution, but show the damaged one to your health care provider.
    It is important that you use your medication exactly as directed. Do not stop your therapy on your own for any reason because your infection could worsen and result in hospitalization. Do not change your dosing schedule without talking to your health care provider. Your health care provider may tell you to stop your infusion if you have a mechanical problem (such as a blockage in the tubing, needle, or catheter); if you have to stop an infusion, call your health care provider immediately so your therapy can continue.

    What SIDE EFFECTS can this medicine cause?

    Penicillin may cause side effects. Tell your health care provider if either of these symptoms is severe or does not go away:
    • upset stomach
    • diarrhea
    If you experience any of the following symptoms, call your health care provider immediately:
    • rash
    • itching
    • fever
    • chills
    • facial swelling
    • wheezing
    • difficulty breathing
    • unusual bleeding or bruising
    • dizziness
    • seizures
    • sore mouth or throat
    If you experience a serious side effect, you or your doctor may send a report to the Food and Drug Administration's (FDA) MedWatch Adverse Event Reporting program online [at http://www.fda.gov/Safety/MedWatch ] or by phone [1-800-332-1088].

    What should I know about STORAGE and DISPOSAL of this medication?

    • Your health care provider probably will give you a several-day supply of penicillin at a time. If you are receiving penicillin intravenously (in your vein), you probably will be told to store it in the refrigerator or freezer.
    • Take your next dose from the refrigerator 1 hour before using it; place it in a clean, dry area to allow it to warm to room temperature.
    • If you are told to store additional penicillin in the freezer, always move a 24-hour supply to the refrigerator for the next day's use.
    • Do not refreeze medications.
    If you are receiving penicillin intramuscularly (in your muscle), your health care provider will tell you how to store it properly.
    Store your medication only as directed. Make sure you understand what you need to store your medication properly.
    Keep your supplies in a clean, dry place when you are not using them, and keep all medications and supplies out of reach of children. Your health care provider will tell you how to throw away used needles, syringes, tubing, and containers to avoid accidental injury.

    What should I do in case of OVERDOSE?

    In case of overdose, call your local poison control center at 1-800-222-1222. If the victim has collapsed or is not breathing, call local emergency services at 911.

    What are the SIGNS OF AN INFECTION?

    If you are receiving penicillin in your vein or under your skin, you need to know the symptoms of a catheter-related infection (an infection where the needle enters your vein or skin). If you experience any of these effects near your intravenous catheter, tell your health care provider as soon as possible:
    • tenderness
    • warmth
    • irritation
    • drainage
    • redness
    • swelling
    • pain

    Brand Names

    • Pfizerpen®

    Dalteparin Sodium Injection

    (dal te pa' rin)

    IMPORTANT WARNING:

    If you have epidural or spinal anesthesia or a spinal puncture while taking a 'blood thinner' such as dalteparin, you are at risk for internal bleeding that could cause you to become paralyzed.
    Tell your doctor if you are taking abciximab (ReoPro); anagrelide (Agrylin); other anticoagulants ('blood thinners') such as warfarin (Coumadin); aspirin, ibuprofen (Advil, Motrin, or Nuprin), indomethacin (Indocin), ketoprofen (Actron, Orudis), naproxen (Aleve, Anaprox, Naprosyn), or other nonsteroidal anti-inflammatory drugs (NSAIDs); cilostazol (Pletal); clopidogrel (Plavix); dipyridamole (Persantine); eptifibatide (Integrilin); sulfinpyrazone (Anturane); ticlopidine (Ticlid); and tirofiban (Aggrastat) .
    If you experience any of the following symptoms, call your doctor immediately: numbness, tingling, leg weakness or paralysis, and loss of control over your bladder or bowels. Talk to your doctor about the risk of taking dalteparin.

    WHY is this medicine prescribed?

    Your doctor has ordered dalteparin sodium, an anticoagulant ('blood thinner'), to prevent harmful blood clots from forming. The drug will be injected under the skin (subcutaneously) once a day. This medication is sometimes prescribed for other uses; ask your doctor or pharmacist for more information.
    Your health care provider (doctor, nurse, or pharmacist) may measure the effectiveness and side effects of your treatment using laboratory tests and physical examinations. It is important to keep all appointments with your doctor and the laboratory. The length of treatment depends on how you respond to the medication.

    What SPECIAL PRECAUTIONS should I follow?

    Before administering dalteparin,
    • tell your doctor and pharmacist if you are allergic to dalteparin, heparin, enoxaparin (Lovenox), any other drugs, or pork products.
    • tell your doctor and pharmacist what prescription and nonprescription medications you are taking, especially those listed in the IMPORTANT WARNING section and vitamins.
    • tell your doctor if you have or have ever had liver or kidney disease or diabetes.
    • tell your doctor if you are pregnant, plan to become pregnant, or are breast-feeding. If you become pregnant while taking dalteparin, call your doctor.

    HOW should this medicine be used?

    Before you administer dalteparin, look at the solution closely. It should be clear and free of floating material. Observe the solution container to make sure there are no leaks. Do not use the solution if it is discolored, if it contains particles, or if the container leaks. Use a new solution, but show the damaged one to your health care provider.
    It is important that you use your medication exactly as directed. Do not change your dosing schedule without talking to your health care provider.

    What SIDE EFFECTS can this medicine cause?

    Dalteparin may cause side effects. Tell your health care provider if the following symptom is severe or does not go away:
    • upset stomach
    If you experience any of the following symptoms or those listed in the IMPORTANT WARNING section, call your doctor or health care provider immediately:
    • unusual bleeding
    • vomiting or spitting up blood or brown material that resembles coffee grounds
    • bloody or black, tarry stools
    • blood in urine
    • red or dark-brown urine
    • easy bruising
    • excessive menstrual bleeding
    • fever
    • dizziness or lightheadedness
    If you experience a serious side effect, you or your doctor may send a report to the Food and Drug Administration's (FDA) MedWatch Adverse Event Reporting program online [at http://www.fda.gov/Safety/MedWatch ] or by phone [1-800-332-1088].

    What should I know about STORAGE and DISPOSAL of this medication?

    • Your health care provider will probably give you several days supply of dalteparin at a time. You will be told to store it at room temperature.
    Store your medication only as directed. Make sure you understand what you need to store your medication properly.
    Keep your supplies in a clean, dry place when you are not using them, and keep all medications and supplies out of reach of children. Your health care provider will tell you how to throw away used needles, syringes, tubing, and containers to avoid accidental injury.

    What should I do in case of OVERDOSE?

    In case of overdose, call your local poison control center at 1-800-222-1222. If the victim has collapsed or is not breathing, call local emergency services at 911.

    What are the SIGNS OF AN INFECTION?

    If you are receiving dalteparin under your skin, you need to know the symptoms of a catheter-related infection (an infection where the needle enters your skin). If you experience any of these effects near the infusion site, tell your health care provider as soon as possible:
    • tenderness
    • warmth
    • irritation
    • drainage
    • redness
    • swelling
    • pain

    Brand Names

    • Fragmin®

    Sodium Chloride (Catheter Flush) Injection

    (so dee um) (klor ide)

    WHY is this medicine prescribed?

    Your doctor has ordered sodium chloride flush to be used to keep your intravenous (IV) catheter from becoming blocked and to remove any medicine from the IV catheter site. It is used each time your IV catheter is used.
    You will probably use a sodium chloride flush several times a day. Your health care provider will determine the number of sodium chloride flushes you will need a day.

    What SPECIAL PRECAUTIONS should I follow?

    Before administering sodium chloride flush,
    • tell your doctor and pharmacist if you are allergic to any medications.
    • tell your doctor and pharmacist what prescription and nonprescription medications you are taking.

    HOW should this medicine be used?

    Before you administer sodium chloride flush, look at the solution closely. It should be clear and free of floating material. Observe the solution container to make sure there are no leaks. Do not use the solution if it is discolored, if it contains particles, or if the container leaks. Use a new solution, but show the damaged one to your health care provider.
    It is important that you use your medication exactly as directed. Do not administer it more often than or for longer periods than your doctor tells you. Do not change your dosing schedule without talking to your health care provider. Your health care provider may tell you to stop your infusion if you have a mechanical problem (such as blockage in the tubing, needle, or catheter); if you have to stop an infusion, call your health care provider immediately so your therapy can continue.

    What SIDE EFFECTS can this medicine cause?

    Sodium chloride flush may cause side effects. Tell your health care provider if the following symptom is severe or does not go away:
    • irritation at the injection site

    What should I know about STORAGE and DISPOSAL of this medication?

    • Your health care provider probably will give you several days supply of sodium chloride. You will be told how to prepare each dose.
    Store your medication only as directed. Make sure you understand what you need to store your medication properly.
    Keep your supplies in a clean, dry place when you are not using them, and keep all medications and supplies out of the reach of children. Your health care provider will tell you how to throw away used needles, syringes, tubing, and containers to avoid accidental injury.

    What are the SIGNS OF AN INFECTION?

    You need to know the symptoms of a catheter-related infection (an infection where the needle enters your vein or skin). If you experience any of these effects near your intravenous catheter, tell your health care provider as soon as possible:
    • tenderness
    • warmth
    • irritation
    • drainage
    • redness
    • swelling
    • pain

    Other Names

    • 0.9% Sodium Chloride
    • Normal Saline

    Foscarnet Sodium Injection

    (fos kar' net)

    WHY is this medicine prescribed?

    Your doctor has ordered foscarnet, an antiviral agent, to help treat your infection. The drug will be added to an intravenous fluid that will drip through a needle or catheter placed in your vein for 1-2 hours, one to three times a day.
    Foscarnet is used to treat cytomegalovirus (CMV) infections in patients whose immune system is not working properly (e.g., patients with acquired immunodeficiency syndrome [AIDS] or organ transplants). These infections include CMV retinitis (an eye infection). This medication is sometimes prescribed for other uses; ask your doctor or pharmacist for more information.
    Your health care provider (doctor, nurse, or pharmacist) may measure the effectiveness and side effects of your treatment using laboratory tests and physical examinations. It is important to keep all appointments with your doctor and the laboratory. The length of treatment depends on how your infection and symptoms respond to the medication.

    What SPECIAL PRECAUTIONS should I follow?

    Before administering foscarnet,
    • tell your doctor and pharmacist if you are allergic to foscarnet or any other drugs.
    • tell your doctor and pharmacist what prescription and nonprescription medications you are taking, especially other antibiotics, probenecid (Benemid), ritonavir (Norvir), saquinavir (Fortovase, Invirase), zidovudine (AZT, Retrovir), and vitamins.
    • tell your doctor if you have or have ever had kidney disease or anemia.
    • tell your doctor if you are pregnant, plan to become pregnant, or are breast-feeding. If you become pregnant while taking foscarnet, call your doctor.

    HOW should this medicine be used?

    Before you administer foscarnet, look at the solution closely. It should be clear and free of floating material. Gently squeeze the bag or observe the solution container to make sure there are no leaks. Do not use the solution if it is discolored, if it contains particles, or if the bag or container leaks. Use a new solution, but show the damaged one to your health care provider.
    It is important that you use your medication exactly as directed. Do not stop your therapy on your own for any reason because your infection could worsen and result in hospitalization. Do not change your dosing schedule without talking to your health care provider. Your health care provider may tell you to stop your infusion if you have a mechanical problem (such as a blockage in the tubing, needle, or catheter); if you have to stop an infusion, call your health care provider immediately so your therapy can continue.

    What SIDE EFFECTS can this medicine cause?

    Foscarnet may cause side effects. The most serious side effect of foscarnet therapy is reduced kidney function. You can prevent this problem by following your doctor's directions concerning drinking plenty of fluids and/or infusing intravenous fluids along with your foscarnet.
    Tell your health care provider if any of these symptoms are severe or do not go away:
    • upset stomach
    • diarrhea
    • vomiting
    • stomach pain
    • loss of appetite
    • confusion
    • dizziness
    • headache
    If you experience any of the following symptoms, call your health care provider immediately:
    • an increase or decrease in frequency of urination
    • an increase or decrease in the amount of urine
    • an increase in thirst
    • fever
    • chills
    • sore throat
    • pain at the injection site
    • seizures
    • muscle twitching
    • pain or numbness in the hands or feet
    • tingling sensation around the mouth
    • unusual tiredness or weakness
    If you experience a serious side effect, you or your doctor may send a report to the Food and Drug Administration's (FDA) MedWatch Adverse Event Reporting program online [at http://www.fda.gov/Safety/MedWatch ] or by phone [1-800-332-1088].

    What should I know about STORAGE and DISPOSAL of this medication?

    • Your health care provider probably will give you several days supply of foscarnet. Store foscarnet at room temperature and out of direct light.
    Store your medication only as directed. Make sure you understand what you need to store your medication properly.
    Keep your supplies in a clean, dry place when you are not using them, and keep all medications and supplies out of reach of children. Your health care provider will tell you how to throw away used needles, syringes, tubing, and containers to avoid accidental injury.

    What should I do in case of OVERDOSE?

    In case of overdose, call your local poison control center at 1-800-222-1222. If the victim has collapsed or is not breathing, call local emergency services at 911.

    What are the SIGNS OF AN INFECTION?

    If you are receiving foscarnet in your vein or under your skin, you need to know the symptoms of a catheter-related infection (an infection where the needle enters your vein or skin). If you experience any of these effects near your intravenous catheter, tell your health care provider as soon as possible:
    • tenderness
    • warmth
    • irritation
    • drainage
    • redness
    • swelling
    • pain

    Brand Names

    • Foscavir®

    Imipenem and Cilastatin Sodium Injection

    (i mi pen' em) (sye la stat' in)

    WHY is this medicine prescribed?

    Your doctor has ordered imipenem and cilastatin, an antibiotic, to help treat your infection. The drug will be either injected into a large muscle (such as your buttock or thigh) or added to an intravenous fluid that will drip through a needle or catheter placed in your vein for about 30 minutes, two to four times a day.
    The combination of imipenem and cilastatin eliminates bacteria that cause many kinds of infections, including pneumonia and gynecological, skin, stomach, blood, bone, joint, urinary tract, and heart valve infections. This medication is sometimes prescribed for other uses; ask your doctor or pharmacist for more information.
    Your health care provider (doctor, nurse, or pharmacist) may measure the effectiveness and side effects of your treatment using laboratory tests and physical examinations. It is important to keep all appointments with your doctor and the laboratory. The length of treatment depends on how your infection and symptoms respond to the medication.

    What SPECIAL PRECAUTIONS should I follow?

    Before administering imipenem and cilastatin,
    • tell your doctor and pharmacist if you are allergic to imipenem, penicillin, cephalosporins [e.g., cefaclor (Ceclor), cefadroxil (Duricef), and cephalexin (Keflex)], or any other drugs.
    • tell your doctor and pharmacist what prescription and nonprescription medications you are taking, especially antibiotics and vitamins.
    • tell your doctor if you have or have ever had seizures; a brain injury; kidney, liver, or gastrointestinal disease (especially colitis); or asthma.
    • tell your doctor if you are pregnant, plan to become pregnant, or are breast-feeding. If you become pregnant while taking imipenem and cilastatin, call your doctor.
    • if you have diabetes and regularly check your urine for sugar, use Clinistix or TesTape. Do not use Clinitest tablets because this drug may cause false positive results.

    HOW should this medicine be used?

    Before you administer imipenem and cilastatin, look at the solution closely. It should be clear and free of floating material. Gently squeeze the bag or observe the solution container to make sure there are no leaks. Do not use the solution if it is discolored, if it contains particles, or if the bag or container leaks. Use a new solution, but show the damaged one to your health care provider.
    It is important that you use your medication exactly as directed. Do not stop your therapy on your own for any reason because your infection could worsen and result in hospitalization. Do not change your dosing schedule without talking to your health care provider. Your health care provider may tell you to stop your infusion if you have a mechanical problem (such as a blockage in the tubing, needle, or catheter); if you have to stop an infusion, call your health care provider immediately so your therapy can continue.

    What SIDE EFFECTS can this medicine cause?

    Imipenem and cilastatin may cause side effects. If you are administering imipenem and cilastatin into a muscle, it probably will be mixed with lidocaine (Xylocaine) to reduce pain at the injection site. Tell your health care provider if any of these symptoms are severe or do not go away:
    • upset stomach
    • vomiting
    • stomach pain
    If you experience any of the following symptoms, call your health care provider immediately:
    • diarrhea
    • rash
    • itching
    • fever
    • chills
    • facial swelling
    • wheezing
    • difficulty breathing
    • unusual bleeding or bruising
    • decreased urination
    • dizziness
    • confusion
    • seizures
    • sore mouth or throat
    If you experience a serious side effect, you or your doctor may send a report to the Food and Drug Administration's (FDA) MedWatch Adverse Event Reporting program online [at http://www.fda.gov/Safety/MedWatch ] or by phone [1-800-332-1088].

    What should I know about STORAGE and DISPOSAL of this medication?

    • Your health care provider probably will give you a several-day supply of imipenem and cilastatin at a time. If you are receiving imipenem and cilastatin intravenously (in your vein), you probably will be told to store it in the refrigerator.
    • Take your next dose from the refrigerator 1 hour before using it; place it in a clean, dry area to allow it to warm to room temperature.
    If you are receiving imipenem and cilastatin intramuscularly (in your muscle), your health care provider will tell you how to store it properly.
    Store your medication only as directed. Make sure you understand what you need to store your medication properly.
    Keep your supplies in a clean, dry place when you are not using them, and keep all medications and supplies out of reach of children. Your health care provider will tell you how to throw away used needles, syringes, tubing, and containers to avoid accidental injury.

    What should I do in case of OVERDOSE?

    In case of overdose, call your local poison control center at 1-800-222-1222. If the victim has collapsed or is not breathing, call local emergency services at 911.

    What are the SIGNS OF AN INFECTION?

    If you are receiving imipenem and cilastatin in your vein or under your skin, you need to know the symptoms of a catheter-related infection (an infection where the needle enters your vein or skin). If you experience any of these effects near your intravenous catheter, tell your health care provider as soon as possible:
    • tenderness
    • warmth
    • irritation
    • drainage
    • redness
    • swelling
    • pain

    Brand Names

    • Primaxin® (as a combination product containing Cilastatin, Imipenem)

    Cefoxitin Sodium Injection

    (se fox' i tin)

    WHY is this medicine prescribed?

    Your doctor has ordered cefoxitin, an antibiotic, to help treat your infection. The drug will be either injected into a large muscle (such as your buttock or hip) or added to an intravenous fluid that will drip through a needle or catheter placed in your vein for 30 minutes, two to four times a day.
    Cefoxitin eliminates bacteria that cause many kinds of infections, including lung, skin, bone, joint, stomach, blood, gynecological, and urinary tract infections. This medication is sometimes prescribed for other uses; ask your doctor or pharmacist for more information.
    Your health care provider (doctor, nurse, or pharmacist) may measure the effectiveness and side effects of your treatment using laboratory tests and physical examinations. It is important to keep all appointments with your doctor and the laboratory. The length of treatment depends on how your infection and symptoms respond to the medication.

    What SPECIAL PRECAUTIONS should I follow?

    Before administering cefoxitin,
    • tell your doctor and pharmacist if you are allergic to cefoxitin, any other cephalosporin [e.g., cefaclor (Ceclor), cefadroxil (Duricef), or cephalexin (Keflex)], penicillins, or any other drugs.
    • tell your doctor and pharmacist what prescription and nonprescription medications you are taking, especially other antibiotics, probenecid (Benemid), and vitamins.
    • tell your doctor if you have or have ever had kidney, liver, or gastrointestinal disease (especially colitis).
    • tell your doctor if you are pregnant, plan to become pregnant, or are breast-feeding. If you become pregnant while taking cefoxitin, call your doctor.
    • if you have diabetes and regularly check your urine for sugar, use Clinistix or TesTape. Do not use Clinitest tablets because cefoxitin may cause false positive results.

    HOW should this medicine be used?

    Before you administer cefoxitin, look at the solution closely. It should be clear and free of floating material. Gently squeeze the bag or observe the solution container to make sure there are no leaks. Do not use the solution if it is discolored, if it contains particles, or if the bag or container leaks. Use a new solution, but show the damaged one to your health care provider.
    It is important that you use your medication exactly as directed. Do not stop your therapy on your own for any reason because your infection could worsen and result in hospitalization. Do not change your dosing schedule without talking to your health care provider. Your health care provider may tell you to stop your infusion if you have a mechanical problem (such as a blockage in the tubing, needle, or catheter); if you have to stop an infusion, call your health care provider immediately so your therapy can continue.

    What SIDE EFFECTS can this medicine cause?

    Cefoxitin may cause side effects. If you are administering cefoxitin into a muscle, it probably will be mixed with lidocaine (Xylocaine) to reduce pain at the injection site. Tell your health care provider if any of these symptoms are severe or do not go away:
    • diarrhea
    • stomach pain
    • upset stomach
    • vomiting
    If you experience any of the following symptoms, call your health care provider immediately:
    • unusual bleeding or bruising
    • difficulty breathing
    • skin rash
    • itching
    • hives
    • sore mouth or throat
    If you experience a serious side effect, you or your doctor may send a report to the Food and Drug Administration's (FDA) MedWatch Adverse Event Reporting program online [at http://www.fda.gov/Safety/MedWatch ] or by phone [1-800-332-1088].

    What should I know about STORAGE and DISPOSAL of this medication?

    • Your health care provider probably will give you a several-day supply of cefoxitin at a time. If you are receiving cefoxitin intravenously (in your vein), you probably will be told to store it in the refrigerator or freezer.
    • Take your next dose from the refrigerator 1 hour before using it; place it in a clean, dry area to allow it to warm to room temperature.
    • If you are told to store additional cefoxitin in the freezer, always move a 24-hour supply to the refrigerator for the next day's use.
    • Do not refreeze medications.
    If you are receiving cefoxitin intramuscularly (in your muscle), your health care provider will tell you how to store it properly.
    Store your medication only as directed. Make sure you understand what you need to store your medication properly.
    Keep your supplies in a clean, dry place when you are not using them, and keep all medications and supplies out of reach of children. Your health care provider will tell you how to throw away used needles, syringes, tubing, and containers to avoid accidental injury.

    What should I do in case of OVERDOSE?

    In case of overdose, call your local poison control center at 1-800-222-1222. If the victim has collapsed or is not breathing, call local emergency services at 911.

    What are the SIGNS OF AN INFECTION?

    If you are receiving cefoxitin in your vein or under your skin, you need to know the symptoms of a catheter-related infection (an infection where the needle enters your vein or skin). If you experience any of these effects near your intravenous catheter, tell your health care provider as soon as possible:
    • tenderness
    • warmth
    • irritation
    • drainage
    • redness
    • swelling
    • pain

    Brand Names

    • Mefoxin®

    Ceftizoxime Sodium Injection

    (sef ti zox' eem)

    IMPORTANT WARNING:

    Ceftizoxime is no longer available in the U.S.

    WHY is this medicine prescribed?

    Your doctor has ordered ceftizoxime, an antibiotic, to help treat your infection. The drug will be either injected into a large muscle (such as your buttock or hip) or added to an intravenous fluid that will drip through a needle or catheter placed in your vein for 30 minutes, two or three times a day.
    Ceftizoxime eliminates bacteria that cause many kinds of infections, including lung, skin, bone, joint, stomach, blood, and urinary tract infections. This medication is sometimes prescribed for other uses; ask your doctor or pharmacist for more information.
    Your health care provider (doctor, nurse, or pharmacist) may measure the effectiveness and side effects of your treatment using laboratory tests and physical examinations. It is important to keep all appointments with your doctor and the laboratory. The length of treatment depends on how your infection and symptoms respond to the medication.

    What SPECIAL PRECAUTIONS should I follow?

    Before administering ceftizoxime,
    • tell your doctor and pharmacist if you are allergic to ceftizoxime, any other cephalosporin [e.g., cefaclor (Ceclor), cefadroxil (Duricef), or cephalexin (Keflex)], penicillins, or any other drugs.
    • tell your doctor and pharmacist what prescription and nonprescription medications you are taking, especially other antibiotics, probenecid (Benemid), and vitamins.
    • tell your doctor if you have or have ever had kidney, liver, or gastrointestinal disease (especially colitis).
    • tell your doctor if you are pregnant, plan to become pregnant, or are breast-feeding. If you become pregnant while taking ceftizoxime, call your doctor.
    • if you have diabetes and regularly check your urine for sugar, use Clinistix or TesTape. Do not use Clinitest tablets because ceftizoxime may cause false positive results.

    HOW should this medicine be used?

    Before you administer ceftizoxime, look at the solution closely. It should be clear and free of floating material. Gently squeeze the bag or observe the solution container to make sure there are no leaks. Do not use the solution if it is discolored, if it contains particles, or if the bag or container leaks. Use a new solution, but show the damaged one to your health care provider.
    It is important that you use your medication exactly as directed. Do not stop your therapy on your own for any reason because your infection could worsen and result in hospitalization. Do not change your dosing schedule without talking to your health care provider. Your health care provider may tell you to stop your infusion if you have a mechanical problem (such as a blockage in the tubing, needle, or catheter); if you have to stop an infusion, call your health care provider immediately so your therapy can continue.

    What SIDE EFFECTS can this medicine cause?

    Ceftizoxime may cause side effects. If you are administering ceftizoxime into a muscle, it may be mixed with lidocaine (Xylocaine) to reduce pain at the injection site. Tell your health care provider if any of these symptoms are severe or do not go away:
    • diarrhea
    • stomach pain
    • upset stomach
    • vomiting
    If you experience any of the following symptoms, call your health care provider immediately:
    • unusual bleeding or bruising
    • difficulty breathing
    • itching
    • rash
    • hives
    • sore mouth or throat
    If you experience a serious side effect, you or your doctor may send a report to the Food and Drug Administration's (FDA) MedWatch Adverse Event Reporting program online [at http://www.fda.gov/Safety/MedWatch ] or by phone [1-800-332-1088].

    What should I know about STORAGE and DISPOSAL of this medication?

    • Your health care provider probably will give you a several-day supply of ceftizoxime at a time. If you are receiving ceftizoxime intravenously (in your vein), you probably will be told to store it in the refrigerator or freezer.
    • Take your next dose from the refrigerator 1 hour before using it; place it in a clean, dry area to allow it to warm to room temperature.
    • If you are told to store additional ceftizoxime in the freezer, always move a 24-hour supply to the refrigerator for the next day's use.
    • Do not refreeze medications.
    If you are receiving ceftizoxime intramuscularly (in your muscle), your health care provider will tell you how to store it properly.
    Store your medication only as directed. Make sure you understand what you need to store your medication properly.
    Keep your supplies in a clean, dry place when you are not using them, and keep all medications and supplies out of reach of children. Your health care provider will tell you how to throw away used needles, syringes, tubing, and containers to avoid accidental injury.

    What should I do in case of OVERDOSE?

    In case of overdose, call your local poison control center at 1-800-222-1222. If the victim has collapsed or is not breathing, call local emergency services at 911.

    What are the SIGNS OF AN INFECTION?

    If you are receiving ceftizoxime in your vein or under your skin, you need to know the symptoms of a catheter-related infection (an infection where the needle enters your vein or skin). If you experience any of these effects near your intravenous catheter, tell your health care provider as soon as possible:
    • tenderness
    • warmth
    • irritation
    • drainage
    • redness
    • swelling
    • pain

    Brand Names

    • Cefizox®

    Ampicillin Sodium Injection

    (am pi sill' in)

    WHY is this medicine prescribed?

    Your doctor has ordered ampicillin, an antibiotic, to help treat your infection. The drug will be either injected into a large muscle (such as your buttock or hip) or added to an intravenous fluid that will drip through a needle or catheter placed in your vein for about 30 minutes, four to six times a day.
    Ampicillin eliminates bacteria that cause many kinds of infection, including pneumonia; meningitis; and urinary tract, gastrointestinal tract, skin, bone, joint, blood, and heart valve infections. This medication is sometimes prescribed for other uses; ask your doctor or pharmacist for more information.
    Your health care provider (doctor, nurse, or pharmacist) may measure the effectiveness and side effects of your treatment using laboratory tests and physical examinations. It is important to keep all appointments with your doctor and the laboratory. The length of treatment depends on how your infection and symptoms respond to the medication.

    What SPECIAL PRECAUTIONS should I follow?

    Before administering ampicillin,
    • tell your doctor and pharmacist if you are allergic to ampicillin, penicillin, cephalosporins [e.g., cefaclor (Ceclor), cefadroxil (Duricef), or cephalexin (Keflex)], or any other drugs.
    • tell your doctor and pharmacist what prescription and nonprescription medications you are taking, especially other antibiotics, allopurinol (Lopurin), anticoagulants ('blood thinners') such as warfarin (Coumadin), atenolol (Tenormin), oral contraceptives, probenecid (Benemid), rifampin (Rifadin), sulfasalazine, and vitamins.
    • tell your doctor if you have or have ever had kidney or liver disease, allergies, asthma, blood disease, colitis, stomach problems, or hay fever.
    • tell your doctor if you are pregnant, plan to become pregnant, or are breast-feeding. If you become pregnant while taking ampicillin, call your doctor.
    • if you have diabetes and regularly check your urine for sugar, use Clinistix or TesTape. Do not use Clinitest tablets because ampicillin may cause false positive results.

    HOW should this medicine be used?

    Before you administer ampicillin, look at the solution closely. It should be clear and free of floating material. Gently squeeze the bag or observe the solution container to make sure there are no leaks. Do not use the solution if it is discolored, if it contains particles, or if the bag or container leaks. Use a new solution, but show the damaged one to your health care provider.
    It is important that you use your medication exactly as directed. Do not stop your therapy on your own for any reason because your infection could worsen and result in hospitalization. Do not change your dosing schedule without talking to your health care provider. Your health care provider may tell you to stop your infusion if you have a mechanical problem (such as a blockage in the tubing, needle, or catheter); if you have to stop an infusion, call your health care provider immediately so your therapy can continue.

    What SIDE EFFECTS can this medicine cause?

    Ampicillin may cause side effects. Tell your doctor if any of these symptoms are severe or do not go away:
    • upset stomach
    • diarrhea
    • vomiting
    • mild skin rash
    If you experience any of the following symptoms, call your health care provider immediately:
    • severe skin rash
    • itching
    • hives
    • difficulty breathing or swallowing
    • wheezing
    • unusual bleeding or bruising
    • headache
    • dizziness
    • seizures
    • sore mouth or throat

    What should I know about STORAGE and DISPOSAL of this medication?

    • Your health care provider probably will give you a several-day supply of ampicillin at a time. If you are receiving ampicillin intravenously (in your vein), you probably will be told to store it in the refrigerator or freezer.
    • Take your next dose from the refrigerator 1 hour before using it; place it in a clean, dry area to allow it to warm to room temperature.
    • If you are told to store additional ampicillin in the freezer, always move a 24-hour supply to the refrigerator for the next day's use.
    • Do not refreeze medications.
    If you are receiving ampicillin intramuscularly (in your muscle), your health care provider will tell you how to store it properly.
    Store your medication only as directed. Make sure you understand what you need to store your medication properly.
    Keep your supplies in a clean, dry place when you are not using them, and keep all medications and supplies out of reach of children. Your health care provider will tell you how to throw away used needles, syringes, tubing, and containers to avoid accidental injury.

    What should I do in case of OVERDOSE?

    In case of overdose, call your local poison control center at 1-800-222-1222. If the victim has collapsed or is not breathing, call local emergency services at 911.

    What are the SIGNS OF AN INFECTION?

    If you are receiving ampicillin in your vein or under your skin, you need to know the symptoms of a catheter-related infection (an infection where the needle enters your vein or skin). If you experience any of these effects near your intravenous catheter, tell your health care provider as soon as possible:
    • tenderness
    • warmth
    • irritation
    • drainage
    • redness
    • swelling
    • pain

    Brand Names

    • Principen®

    Nafcillin Sodium Injection

    (naf sill' in)

    WHY is this medicine prescribed?

    Your doctor has ordered nafcillin, an antibiotic, to help treat your infection. The drug will be either injected into a large muscle (such as your buttock or hip) or added to an intravenous fluid that will drip through a needle or catheter placed in your vein for 30-60 minutes, four to six times a day.
    Nafcillin eliminates bacteria that cause infections, including pneumonia; meningitis; and urinary tract, skin, bone, joint, blood, and heart valve infections. This medication is sometimes prescribed for other uses; ask your doctor or pharmacist for more information.
    Your health care provider (doctor, nurse, or pharmacist) may measure the effectiveness and side effects of your treatment using laboratory tests and physical examinations. It is important to keep all appointments with your doctor and the laboratory. The length of treatment depends on how your infection and symptoms respond to the medication.

    What SPECIAL PRECAUTIONS should I follow?

    Before administering nafcillin,
    • tell your doctor and pharmacist if you are allergic to nafcillin, penicillin, cephalosporins [e.g., cefaclor (Ceclor), cefadroxil (Duricef), or cephalexin (Keflex)], or any other drugs.
    • tell your doctor and pharmacist what prescription and nonprescription medications you are taking, especially antibiotics and vitamins.
    • tell your doctor if you have or have ever had asthma; hay fever; or kidney, liver, or gastrointestinal disease (especially colitis).
    • tell your doctor if you are pregnant, plan to become pregnant, or are breast-feeding. If you become pregnant while taking nafcillin, call your doctor.
    • if you have diabetes and regularly check your urine for sugar, use Clinistix or TesTape. Do not use Clinitest tablets because nafcillin may cause false positive results.

    HOW should this medicine be used?

    Before you administer nafcillin, look at the solution closely. It should be clear and free of floating material. Gently squeeze the bag or observe the solution container to make sure there are no leaks. Do not use the solution if it is discolored, if it contains particles, or if the bag or container leaks. Use a new solution, but show the damaged one to your health care provider.
    It is important that you use your medication exactly as directed. Do not stop your therapy on your own for any reason because your infection could worsen and result in hospitalization. Do not change your dosing schedule without talking to your health care provider. Your health care provider may tell you to stop your infusion if you have a mechanical problem (such as a blockage in the tubing, needle, or catheter); if you have to stop an infusion, call your health care provider immediately so your therapy can continue.

    What SIDE EFFECTS can this medicine cause?

    Nafcillin may cause side effects. Tell your health care provider if either of these symptoms is severe or does not go away:
    • upset stomach
    • diarrhea
    If you experience any of the following symptoms, call your health care provider immediately:
    • rash
    • itching
    • fever
    • chills
    • facial swelling
    • wheezing
    • difficulty breathing
    • unusual bleeding or bruising
    • dizziness
    • seizures
    • sore mouth or throat
    If you experience a serious side effect, you or your doctor may send a report to the Food and Drug Administration's (FDA) MedWatch Adverse Event Reporting program online [at http://www.fda.gov/Safety/MedWatch ] or by phone [1-800-332-1088].

    What should I know about STORAGE and DISPOSAL of this medication?

    • Your health care provider probably will give you a several-day supply of nafcillin at a time. If you are receiving nafcillin intravenously (in your vein), you probably will be told to store it in the refrigerator or freezer.
    • Take your next dose from the refrigerator 1 hour before using it; place it in a clean, dry area to allow it to warm to room temperature.
    • If you are told to store additional nafcillin in the freezer, always move a 24-hour supply to the refrigerator for the next day's use.
    • Do not refreeze medications.
    If you are receiving nafcillin intramuscularly (in your muscle), your health care provider will tell you how to store it properly.
    Store your medication only as directed. Make sure you understand what you need to store your medication properly.
    Keep your supplies in a clean, dry place when you are not using them, and keep all medications and supplies out of reach of children. Your health care provider will tell you how to throw away used needles, syringes, tubing, and containers to avoid accidental injury.

    What should I do in case of OVERDOSE?

    In case of overdose, call your local poison control center at 1-800-222-1222. If the victim has collapsed or is not breathing, call local emergency services at 911.

    What are the SIGNS OF AN INFECTION?

    If you are receiving nafcillin in your vein or under your skin, you need to know the symptoms of a catheter-related infection (an infection where the needle enters your vein or skin). If you experience any of these effects near your intravenous catheter, tell your health care provider as soon as possible:
    • tenderness
    • warmth
    • irritation
    • drainage
    • redness
    • swelling
    • pain

    Brand Names

    • Unipen®

    Oxacillin Sodium Injection

    (ox a sill' in)

    WHY is this medicine prescribed?

    Your doctor has ordered oxacillin, an antibiotic, to help treat your infection. The drug will be either injected into a large muscle (such as your buttock or hip) or added to an intravenous fluid that will drip through a needle or catheter placed in your vein for about 30 minutes, four to six times a day.
    Oxacillin eliminates bacteria that cause infections, including pneumonia; meningitis; and urinary tract, skin, bone, joint, blood, and heart valve infections. This medication is sometimes prescribed for other uses; ask your doctor or pharmacist for more information.
    Your health care provider (doctor, nurse, or pharmacist) may measure the effectiveness and side effects of your treatment using laboratory tests and physical examinations. It is important to keep all appointments with your doctor and the laboratory. The length of treatment depends on how your infection and symptoms respond to the medication.

    What SPECIAL PRECAUTIONS should I follow?

    Before administering oxacillin,
    • tell your doctor and pharmacist if you are allergic to oxacillin, penicillin, cephalosporins [e.g., cefaclor (Ceclor), cefadroxil (Duricef), or cephalexin (Keflex)], or any other drugs.
    • tell your doctor and pharmacist what prescription and nonprescription medications you are taking, especially antibiotics and vitamins.
    • tell your doctor if you have or have ever had asthma; hay fever; or kidney, liver, or gastrointestinal disease (especially colitis).
    • tell your doctor if you are pregnant, plan to become pregnant, or are breast-feeding. If you become pregnant while taking oxacillin, call your doctor.
    • if you have diabetes and regularly check your urine for sugar, use Clinistix or TesTape. Do not use Clinitest tablets because oxacillin may cause false positive results.

    HOW should this medicine be used?

    Before you administer oxacillin, look at the solution closely. It should be clear and free of floating material. Gently squeeze the bag or observe the solution container to make sure there are no leaks. Do not use the solution if it is discolored, if it contains particles, or if the bag or container leaks. Use a new solution, but show the damaged one to your health care provider.
    It is important that you use your medication exactly as directed. Do not stop your therapy on your own for any reason because your infection could worsen and result in hospitalization. Do not change your dosing schedule without talking to your health care provider. Your health care provider may tell you to stop your infusion if you have a mechanical problem (such as a blockage in the tubing, needle, or catheter); if you have to stop an infusion, call your health care provider immediately so your therapy can continue.

    What SIDE EFFECTS can this medicine cause?

    Oxacillin may cause side effects. Tell your health care provider if either of these symptoms is severe or does not go away:
    • upset stomach
    • diarrhea
    If you experience any of the following symptoms, call your health care provider immediately:
    • rash
    • itching
    • fever
    • chills
    • facial swelling
    • wheezing
    • difficulty breathing
    • unusual bleeding or bruising
    • dizziness
    • seizures
    • sore mouth or throat
    If you experience a serious side effect, you or your doctor may send a report to the Food and Drug Administration's (FDA) MedWatch Adverse Event Reporting program online [at http://www.fda.gov/Safety/MedWatch ] or by phone [1-800-332-1088].

    What should I know about STORAGE and DISPOSAL of this medication?

    • Your health care provider probably will give you a several-day supply of oxacillin at a time. If you are receiving oxacillin intravenously (in your vein), you probably will be told to store it in the refrigerator or freezer.
    • Take your next dose from the refrigerator 1 hour before using it; place it in a clean, dry area to allow it to warm to room temperature.
    • If you are told to store additional oxacillin in the freezer, always move a 24-hour supply to the refrigerator for the next day's use.
    • Do not refreeze medications.
    If you are receiving oxacillin intramuscularly (in your muscle), your health care provider will tell you how to store it properly.
    Store your medication only as directed. Make sure you understand what you need to store your medication properly.
    Keep your supplies in a clean, dry place when you are not using them, and keep all medications and supplies out of reach of children. Your health care provider will tell you how to throw away used needles, syringes, tubing, and containers to avoid accidental injury.

    What should I do in case of OVERDOSE?

    In case of overdose, call your local poison control center at 1-800-222-1222. If the victim has collapsed or is not breathing, call local emergency services at 911.

    What are the SIGNS OF AN INFECTION?

    If you are receiving oxacillin in your vein or under your skin, you need to know the symptoms of a catheter-related infection (an infection where the needle enters your vein or skin). If you experience any of these effects near your intravenous catheter, tell your health care provider as soon as possible:
    • tenderness
    • warmth
    • irritation
    • drainage
    • redness
    • swelling
    • pain

    Brand Names

    • Bactocill®

    Methylprednisolone Sodium Succinate Injection

    (meth il pred nis' oh lone)

    WHY is this medicine prescribed?

    Your doctor has ordered methylprednisolone, a corticosteroid, to relieve inflammation (swelling, heat, redness, and pain). The drug will be added to an intravenous fluid that will drip through a needle or catheter placed in your vein for at least 1 hour per day.
    Methylprednisolone is similar to a natural hormone produced by your adrenal glands. It is used to treat, but not cure, certain forms of arthritis; skin, blood, kidney, eye, thyroid, and intestinal disorders (e.g., colitis); and multiple sclerosis. This medication is sometimes prescribed for other uses; ask your doctor or pharmacist for more information.
    Your healthcare provider (doctor, nurse, or pharmacist) may measure the effectiveness and side effects of your treatment using laboratory tests and physical examinations. It is important to keep all appointments with your doctor and the laboratory. The length of treatment depends on how you respond to the medication.

    What SPECIAL PRECAUTIONS should I follow?

    Before administering methylprednisolone,
    • tell your doctor and pharmacist if you are allergic to methylprednisolone, aspirin, or any other drugs.
    • tell your doctor and pharmacist what prescription and nonprescription medications you are taking, especially anticoagulants ('blood thinners') such as warfarin (Coumadin), arthritis medications, aspirin, azithromycin (Zithromax), clarithromycin (Biaxin), cyclosporine (Neoral, Sandimmune), digoxin (Lanoxin), diuretics ('water pills'), erythromycin, estrogen (Premarin), ketoconazole (Nizoral), oral contraceptives, phenobarbital, phenytoin (Dilantin), rifampin (Rifadin), theophylline (Theo-Dur), and vitamins.
    • tell your doctor if you have a fungal infection (other than on your skin); do not use methylprednisolone without talking to your doctor.
    • tell your doctor if you have or have ever had liver, kidney, intestinal, or heart disease; diabetes; an underactive thyroid gland; high blood pressure; mental illness; myasthenia gravis; osteoporosis; herpes eye infection; seizures; tuberculosis (TB); or ulcers.
    • tell your doctor if you are pregnant, plan to become pregnant, or are breast-feeding. If you become pregnant while using methylprednisolone, call your doctor.
    • if you are having surgery, including dental surgery, tell the doctor or dentist that you are using methylprednisolone.

    HOW should this medicine be used?

    Before you administer methylprednisolone, look at the solution closely. It should be clear and free of floating material. Gently squeeze the bag or observe the solution container to make sure there are no leaks. Do not use the solution if it is discolored, if it contains particles, or if the bag or container leaks. Use a new solution, but show the damaged one to your healthcare provider.
    It is important that you use your medication exactly as directed. Do not change your dosing schedule without talking to your healthcare provider. Your healthcare provider may tell you to stop your infusion if you have a mechanical problem (such as a blockage in the tubing, needle, or catheter); if you have to stop an infusion, call your healthcare provider immediately so your therapy can continue.

    What SIDE EFFECTS can this medicine cause?

    Methylprednisolone may cause side effects. Tell your doctor if any of these symptoms are severe or do not go away:
    • headache
    • dizziness
    • insomnia
    • restlessness
    • depression
    • anxiety
    • unusual moods
    • increased sweating
    • increased hair growth
    • reddened face
    • acne
    • thinned skin
    • easy bruising
    • tiny purple skin spots
    • irregular or absent menstrual periods
    If you experience any of the following symptoms, call your doctor immediately:
    • swollen feet, ankles, and lower legs
    • muscle pain and weakness
    • eye pain
    • vision problems
    • puffy skin (especially the face)
    • a cold or infection that lasts a long time

    What should I know about STORAGE and DISPOSAL of this medication?

    Your healthcare provider probably will give you a several-day supply of methylprednisolone at a time. You will be told how to prepare each dose.
    Store your medication only as directed. Make sure you understand what you need to store your medication properly.
    Keep your supplies in a clean, dry place when you are not using them, and keep all medications and supplies out of reach of children. Your healthcare provider will tell you how to throw away used needles, syringes, tubing, and containers to avoid accidental injury.

    What should I do in case of OVERDOSE?

    In case of overdose, call your local poison control center at 1-800-222-1222. If the victim has collapsed or is not breathing, call local emergency services at 911.

    What are the SIGNS OF AN INFECTION?

    If you are receiving methylprednisolone in your vein or under your skin, you need to know the symptoms of a catheter-related infection (an infection where the needle enters your vein or skin). If you experience any of these effects near your intravenous catheter, tell your healthcare provider as soon as possible:
    • tenderness
    • warmth
    • irritation
    • drainage
    • redness
    • swelling
    • pain

    Brand Names

    • A-methaPred®
    • Depo-Medrol®
    • Solu-Medrol®

    Cefazolin Sodium Injection

    (sef a' zoe lin)

    WHY is this medicine prescribed?

    Your doctor has ordered cefazolin, an antibiotic, to help treat your infection. The drug will be either injected into a large muscle (such as your buttock or hip) or added to an intravenous fluid that will drip through a needle or catheter placed in your vein for 30 minutes, two to four times a day.
    Cefazolin eliminates bacteria that cause many kinds of infections, including lung, skin, bone, joint, stomach, blood, heart valve, and urinary tract infections. This medication is sometimes prescribed for other uses; ask your doctor or pharmacist for more information.
    Your health care provider (doctor, nurse, or pharmacist) may measure the effectiveness and side effects of your treatment using laboratory tests and physical examinations. It is important to keep all appointments with your doctor and the laboratory. The length of treatment depends on how your infection and symptoms respond to the medication.

    What SPECIAL PRECAUTIONS should I follow?

    Before administering cefazolin,
    • tell your doctor and pharmacist if you are allergic to cefazolin, any other cephalosporin [e.g., cefaclor (Ceclor), cefadroxil (Duricef), or cephalexin (Keflex)], penicillins, or any other drugs.
    • tell your doctor and pharmacist what prescription and nonprescription medications you are taking, especially other antibiotics, probenecid (Benemid), and vitamins.
    • tell your doctor if you have or have ever had kidney, liver, or gastrointestinal disease (especially colitis).
    • tell your doctor if you are pregnant, plan to become pregnant, or are breast-feeding. If you become pregnant while taking cefazolin, call your doctor.
    • if you have diabetes and regularly check your urine for sugar, use Clinistix or TesTape. Do not use Clinitest tablets because cefazolin may cause false positive results.

    HOW should this medicine be used?

    Before you administer cefazolin, look at the solution closely. It should be clear and free of floating material. Gently squeeze the bag or observe the solution container to make sure there are no leaks. Do not use the solution if it is discolored, if it contains particles, or if the bag or container leaks. Use a new solution, but show the damaged one to your health care provider.
    It is important that you use your medication exactly as directed. Do not stop your therapy on your own for any reason because your infection could worsen and result in hospitalization. Do not change your dosing schedule without talking to your health care provider. Your health care provider may tell you to stop your infusion if you have a mechanical problem (such as a blockage in the tubing, needle, or catheter); if you have to stop an infusion, call your health care provider immediately so your therapy can continue.

    What SIDE EFFECTS can this medicine cause?

    Cefazolin may cause side effects. Tell your health care provider if any of these symptoms are severe or do not go away:
    • diarrhea
    • stomach pain
    • upset stomach
    • vomiting
    If you experience any of the following symptoms, call your health care provider immediately:
    • skin rash
    • itching
    • hives
    • unusual bleeding or bruising
    • difficulty breathing
    • sore mouth or throat
    If you experience a serious side effect, you or your doctor may send a report to the Food and Drug Administration's (FDA) MedWatch Adverse Event Reporting program online [at http://www.fda.gov/Safety/MedWatch ] or by phone [1-800-332-1088].

    What should I know about STORAGE and DISPOSAL of this medication?

    • Your health care provider probably will give you a several-day supply of cefazolin at a time. If you are receiving cefazolin intravenously (in your vein), you probably will be told to store it in the refrigerator or freezer.
    • Take your next dose from the refrigerator 1 hour before using it; place it in a clean, dry area to allow it to warm to room temperature.
    • If you are told to store additional cefazolin in the freezer, always move a 24-hour supply to the refrigerator for the next day's use.
    • Do not refreeze medications.
    If you are receiving cefazolin intramuscularly (in your muscle), your health care provider will tell you how to store it properly.
    Store your medication only as directed. Make sure you understand what you need to store your medication properly.
    Keep your supplies in a clean, dry place when you are not using them, and keep all medications and supplies out of reach of children. Your health care provider will tell you how to throw away used needles, syringes, tubing, and containers to avoid accidental injury.

    What should I do in case of OVERDOSE?

    In case of overdose, call your local poison control center at 1-800-222-1222. If the victim has collapsed or is not breathing, call local emergency services at 911.

    What are the SIGNS OF AN INFECTION?

    If you are receiving cefazolin in your vein or under your skin, you need to know the symptoms of a catheter-related infection (an infection where the needle enters your vein or skin). If you experience any of these effects near your intravenous catheter, tell your health care provider as soon as possible:
    • tenderness
    • warmth
    • irritation
    • drainage
    • redness
    • swelling
    • pain

    Brand Names

    • Ancef®

    Cefotaxime Sodium Injection

    (sef oh taks' eem)

    WHY is this medicine prescribed?

    Your doctor has ordered cefotaxime, an antibiotic, to help treat your infection. The drug will be either injected into a large muscle (such as your buttock or hip) or added to an intravenous fluid that will drip through a needle or catheter placed in your vein for 30 minutes, two to four times a day.
    Cefotaxime eliminates bacteria that cause many kinds of infections, including lung, skin, bone, joint, stomach, blood, gynecological, and urinary tract infections. This medication is sometimes prescribed for other uses; ask your doctor or pharmacist for more information.
    Your health care provider (doctor, nurse, or pharmacist) may measure the effectiveness and side effects of your treatment using laboratory tests and physical examinations. It is important to keep all appointments with your doctor and the laboratory. The length of treatment depends on how your infection and symptoms respond to the medication.

    What SPECIAL PRECAUTIONS should I follow?

    Before administering cefotaxime,
    • tell your doctor and pharmacist if you are allergic to cefotaxime, any other cephalosporin [e.g., cefaclor (Ceclor), cefadroxil (Duricef), or cephalexin (Keflex)], penicillins, or any other drugs.
    • tell your doctor and pharmacist what prescription and nonprescription medications you are taking, especially other antibiotics, probenecid (Benemid), and vitamins.
    • tell your doctor if you have or have ever had kidney, liver, or gastrointestinal disease (especially colitis).
    • tell your doctor if you are pregnant, plan to become pregnant, or are breast-feeding. If you become pregnant while taking cefotaxime, call your doctor.

    HOW should this medicine be used?

    Before you administer cefotaxime, look at the solution closely. It should be clear and free of floating material. Gently squeeze the bag or observe the solution container to make sure there are no leaks. Do not use the solution if it is discolored, if it contains particles, or if the bag or container leaks. Use a new solution, but show the damaged one to your health care provider.
    It is important that you use your medication exactly as directed. Do not stop your therapy on your own for any reason because your infection could worsen and result in hospitalization. Do not change your dosing schedule without talking to your health care provider. Your health care provider may tell you to stop your infusion if you have a mechanical problem (such as a blockage in the tubing, needle, or catheter); if you have to stop an infusion, call your health care provider immediately so your therapy can continue.

    What SIDE EFFECTS can this medicine cause?

    Cefotaxime may cause side effects. Tell your health care provider if any of these symptoms are severe or do not go away:
    • diarrhea
    • stomach pain
    • upset stomach
    • vomiting
    If you experience any of the following symptoms, call your health care provider immediately:
    • unusual bleeding or bruising
    • difficulty breathing
    • skin rash
    • itching
    • hives
    • sore mouth or throat
    If you experience a serious side effect, you or your doctor may send a report to the Food and Drug Administration's (FDA) MedWatch Adverse Event Reporting program online [at http://www.fda.gov/Safety/MedWatch ] or by phone [1-800-332-1088].

    What should I know about STORAGE and DISPOSAL of this medication?

    • Your health care provider probably will give you a several-day supply of cefotaxime at a time. If you are receiving cefotaxime intravenously (in your vein), you probably will be told to store it in the refrigerator or freezer.
    • Take your next dose from the refrigerator 1 hour before using it; place it in a clean, dry area to allow it to warm to room temperature.
    • If you are told to store additional cefotaxime in the freezer, always move a 24-hour supply to the refrigerator for the next day's use.
    • Do not refreeze medications.
    If you are receiving cefotaxime intramuscularly (in your muscle), your health care provider will tell you how to store it properly.
    Store your medication only as directed. Make sure you understand what you need to store your medication properly.
    Keep your supplies in a clean, dry place when you are not using them, and keep all medications and supplies out of reach of children. Your health care provider will tell you how to throw away used needles, syringes, tubing, and containers to avoid accidental injury.

    What should I do in case of OVERDOSE?

    In case of overdose, call your local poison control center at 1-800-222-1222. If the victim has collapsed or is not breathing, call local emergency services at 911.

    What are the SIGNS OF AN INFECTION?

    If you are receiving cefotaxime in your vein or under your skin, you need to know the symptoms of a catheter-related infection (an infection where the needle enters your vein or skin). If you experience any of these effects near your intravenous catheter, tell your health care provider as soon as possible:
    • tenderness
    • warmth
    • irritation
    • drainage
    • redness
    • swelling
    • pain

    Brand Names

    • Claforan®

    Cefuroxime Sodium Injection

    (se fyoor ox' eem)

    WHY is this medicine prescribed?

    Your doctor has ordered cefuroxime, an antibiotic, to help treat your infection. The drug will be either injected into a large muscle (such as your buttock or hip) or added to an intravenous fluid that will drip through a needle or catheter placed in your vein for 30 minutes, two to four times a day.
    Cefuroxime eliminates bacteria that cause many kinds of infections, including lung, skin, bone, joint, stomach, blood, and urinary tract infections. This medication is sometimes prescribed for other uses; ask your doctor or pharmacist for more information.
    Your health care provider (doctor, nurse, or pharmacist) may measure the effectiveness and side effects of your treatment using laboratory tests and physical examinations. It is important to keep all appointments with your doctor and the laboratory. The length of treatment depends on how your infection and symptoms respond to the medication.

    What SPECIAL PRECAUTIONS should I follow?

    Before administering cefuroxime,
    • tell your doctor and pharmacist if you are allergic to cefuroxime, any other cephalosporin [e.g., cefaclor (Ceclor), cefadroxil (Duricef), or cephalexin (Keflex)], penicillins, or any other drugs.
    • tell your doctor and pharmacist what prescription and nonprescription medications you are taking, especially other antibiotics, probenecid (Benemid), and vitamins.
    • tell your doctor if you have or have ever had kidney, liver, or gastrointestinal disease (especially colitis).
    • tell your doctor if you are pregnant, plan to become pregnant, or are breast-feeding. If you become pregnant while taking cefuroxime, call your doctor.
    • if you have diabetes and regularly check your urine for sugar, use Clinistix or TesTape. Do not use Clinitest tablets because cefuroxime may cause false positive results.

    HOW should this medicine be used?

    Before you administer cefuroxime, look at the solution closely. It should be clear and free of floating material. Gently squeeze the bag or observe the solution container to make sure there are no leaks. Do not use the solution if it is discolored, if it contains particles, or if the bag or container leaks. Use a new solution, but show the damaged one to your health care provider.
    It is important that you use your medication exactly as directed. Do not stop your therapy on your own for any reason because your infection could worsen and result in hospitalization. Do not change your dosing schedule without talking to your health care provider. Your health care provider may tell you to stop your infusion if you have a mechanical problem (such as a blockage in the tubing, needle, or catheter); if you have to stop an infusion, call your health care provider immediately so your therapy can continue.

    What SIDE EFFECTS can this medicine cause?

    Cefuroxime may cause side effects. Tell your health care provider if any of these symptoms are severe or do not go away:
    • diarrhea
    • stomach pain
    • upset stomach
    • vomiting
    If you experience any of the following symptoms, call your health care provider immediately:
    • unusual bleeding or bruising
    • difficulty breathing
    • itching
    • rash
    • hives
    • sore mouth or throat
    If you experience a serious side effect, you or your doctor may send a report to the Food and Drug Administration's (FDA) MedWatch Adverse Event Reporting program online [at http://www.fda.gov/Safety/MedWatch ] or by phone [1-800-332-1088].

    What should I know about STORAGE and DISPOSAL of this medication?

    • Your health care provider probably will give you a several-day supply of cefuroxime at a time. If you are receiving cefuroxime intravenously (in your vein), you probably will be told to store it in the refrigerator or freezer.
    • Take your next dose from the refrigerator 1 hour before using it; place it in a clean, dry area to allow it to warm to room temperature.
    • If you are told to store additional cefuroxime in the freezer, always move a 24-hour supply to the refrigerator for the next day's use.
    • Do not refreeze medications.
    If you are receiving cefuroxime intramuscularly (in your muscle), your health care provider will tell you how to store it properly.
    Store your medication only as directed. Make sure you understand what you need to store your medication properly.
    Keep your supplies in a clean, dry place when you are not using them, and keep all medications and supplies out of reach of children. Your health care provider will tell you how to throw away used needles, syringes, tubing, and containers to avoid accidental injury.

    What should I do in case of OVERDOSE?

    In case of overdose, call your local poison control center at 1-800-222-1222. If the victim has collapsed or is not breathing, call local emergency services at 911.

    What are the SIGNS OF AN INFECTION?

    If you are receiving cefuroxime in your vein or under your skin, you need to know the symptoms of a catheter-related infection (an infection where the needle enters your vein or skin). If you experience any of these effects near your intravenous catheter, tell your health care provider as soon as possible:
    • tenderness
    • warmth
    • irritation
    • drainage
    • redness
    • swelling
    • pain

    Brand Names

    • Zinacef®

    Famotidine Injection

    (fa moe' ti deen)

    WHY is this medicine prescribed?

    Your doctor has ordered famotidine to decrease the amount of acid your stomach makes. It is used to treat and prevent ulcers and to treat other conditions in which the stomach makes too much acid. The drug will be either added to an intravenous fluid that will drip through a needle or catheter placed in your vein for at least 15 minutes, once or twice a day, or administered by constant infusion over 24 hours. This medication is sometimes prescribed for other uses; ask your doctor or pharmacist for more information.
    Your health care provider (doctor, nurse, or pharmacist) may measure the effectiveness and side effects of your treatment using laboratory tests and physical examinations. It is important to keep all appointments with your doctor and the laboratory. The length of treatment depends on how you respond to the medication.

    What SPECIAL PRECAUTIONS should I follow?

    Before administering famotidine,
    • tell your doctor and pharmacist if you are allergic to famotidine, cimetidine (Tagamet), nizatidine (Axid), ranitidine (Zantac), or any other drugs.
    • tell your doctor and pharmacist what prescription and nonprescription medications you are taking, including vitamins.
    • tell your doctor if you have or have ever had kidney or liver disease.
    • tell your doctor if you are pregnant, plan to become pregnant, or are breast-feeding. If you become pregnant while taking famotidine, call your doctor.

    HOW should this medicine be used?

    Before you administer famotidine, look at the solution closely. It should be clear and free of floating material. Gently squeeze the bag or observe the solution container to make sure there are no leaks. Do not use the solution if it is discolored, if it contains particles, or if the bag or container leaks. Use a new solution, but show the damaged one to your health care provider.
    It is important that you use your medication exactly as directed. Do not change your dosing schedule without talking to your health care provider. Your health care provider may tell you to stop your infusion if you have a mechanical problem (such as a blockage in the tubing, needle, or catheter); if you have to stop an infusion, call your health care provider immediately so your therapy can continue.

    What SIDE EFFECTS can this medicine cause?

    Famotidine may cause side effects. Tell your health care provider if any of these symptoms are severe or do not go away:
    • headache
    • dizziness
    • constipation
    • diarrhea

    What should I know about STORAGE and DISPOSAL of this medication?

    • Your health care provider probably will give you a several-day supply of famotidine at a time. If you are receiving famotidine intravenously (in your vein), you probably will be told to store it in the refrigerator or freezer.
    • Take your next dose from the refrigerator 1 hour before using it; place it in a clean, dry area to allow it to warm to room temperature.
    • If you are told to store additional famotidine in the freezer, always move a 24-hour supply to the refrigerator for the next day's use.
    • Do not refreeze medications.
    Store your medication only as directed. Make sure you understand what you need to store your medication properly.
    Keep your supplies in a clean, dry place when you are not using them, and keep all medications and supplies out of reach of children. Your health care provider will tell you how to throw away used needles, syringes, tubing, and containers to avoid accidental injury.

    What should I do in case of OVERDOSE?

    In case of overdose, call your local poison control center at 1-800-222-1222. If the victim has collapsed or is not breathing, call local emergency services at 911.

    What are the SIGNS OF AN INFECTION?

    If you are receiving famotidine in your vein or under your skin, you need to know the symptoms of a catheter-related infection (an infection where the needle enters your vein or skin). If you experience any of these effects near your intravenous catheter, tell your health care provider as soon as possible:
    • tenderness
    • warmth
    • irritation
    • drainage
    • redness
    • swelling
    • pain

    Brand Names

    • Pepcid® I.V.
    • Pepcid® Premixed in Iso-osmotic Sodium Chloride Injection
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