• Symptoms of Scleroderma

    Symptoms of scleroderma include:
      Raynaud’s phenomenon :
      • Changes in skin color of the fingertips, toes, and nose in response to cold or emotional stress
      • Skin usually turns very white when first exposed to cold, then blue, then very red
      • May be accompanied by pain, tingling, numbness
    • Sores or ulcers on the fingers
    • Changes in the skin, as areas of affected skin lose hair and become:
      • Stiff
      • Hard
      • Thick
      • Shiny
      • Darker or lighter with darker spots (the so-called salt and pepper appearance)
    • Skin over face may become so tight that it’s hard to change expression (face appears “mask-like”)
    • Fingers and toes become swollen or puffy
    • Whitish bumps of calcium deposits develop under the skin (calcinosis)
    • Tiny purplish-red blood vessels appear under the skin (telangiectasias)
    • Skin creases diminish or disappear
    • Arthritis (joint aches and stiffness)
    • Muscle pain and weakness
    • Dry eyes and mouth (called Sjögren’s syndrome )
    • Digestive problems: Problems due to lung, heart, and kidney involvement:

    References

    Feldman M, et al. Sleisenger & Fordtran's Gastrointestinal and Liver Disease . 8th ed. St. Louis, MO: Mosby; 2005.

    Ferri F ed. Ferri’s Clinical Advisor 2011 . 1st ed. Philadelphia, PA: Mosby Elsevier; 2010.

    Firestein ED et al. Kelley’s Textbook of Rheumatology . 8th ed. Philadelphia, PA: Saunders; 2008.

    Goldman L, Ausiello D, eds. Cecil Textbook of Internal Medicine . 23rd ed. Philadelphia, PA: Saunders; 2008.

    Habif TP. Clinical Dermatology . 4th ed. St. Louis, MO: Mosby; 2004.

    Harrison’s Principles of Internal Medicine . 15th ed. McGraw Hill; 2001.

    National Institute of Arthritis and Musculoskeletal and Skin Diseases website. Available at: http://www.niams.nih.gov/ .

    Noble J. Textbook of Primary Care Medicine . 3rd ed. St. Louis, MO: Mosby; 2000.

    Rakel R. Textbook of Family Medicine 2007. 7th ed. Philadelphia, PA: Saunders Elsevier; 2009.

    Rakel RE, Bope ET. Conn's Current Therapy . 60th ed. Philadelphia, PA: Saunders Elsevier; 2009.

    Scleroderma Foundation website. Available at: http://www.scleroderma.org/ .

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