• Amiodarone

    Trade Names :

    • Cordarone
    • Pacerone
    Vitamin E - May Protect Against Side Effects Chaparral, Comfrey, and Coltsfoot - Possible Harmful Interaction St. John's Wort, Dong Quai - Possible Harmful Interaction
    Amiodarone is used to restore normal heart rhythm.
    Vitamin E
    One of the problems with amiodarone is that it can cause injury to the lungs. One study suggests that vitamin E supplements might help prevent this side effect. 1
    The herbs chaparral ( Larrea tridentata or L. mexicana ), comfrey (Symphytum officinale), and coltsfoot (Tussilago farfara) contain liver-toxic substances. Because amiodarone can also be hard on the liver, combining these herbs with the medication is not advisable.
    Dong QuaiSt. John's Wort
    Amiodarone has been reported to cause increased sensitivity to the sun, amplifying the risk of sunburn or skin rash. Because St. John's wort and dong quai may also cause this problem, taking these herbal supplements during amiodarone therapy might add to this risk.
    It may be a good idea to wear a sunscreen or protective clothing during sun exposure if you take one of these herbs while using amiodarone.


    1 Kachel DL, et al. Amiodarone-induced injury of human pulmonary artery endothelial cells: Protection by alpha-tocopherol. J Pharmacol Exp Ther 254: 1107–1112, 1990.

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