• Hydronephrosis—Adult


    Hydronephros is a build-up of urine in the kidneys. The kidney tubes swell from the excess urine pressure. It can happen when urine cannot drain into the bladder of if the bladder not draining well. The condition may affect one or both kidneys. Hydronephrosis is not a disease, but a symptom of a problem with the urinary system.
    Kidney, Ureter, Bladder, and Kidney Stone
    Copyright © Nucleus Medical Media, Inc.


    Hydronephrosis in adults is usually caused by a blockage, which can occur with many types of obstruction, such as:
    • Kidney stones
    • Blood clots
    • Abnormal growths
    • Scar tissue from an injury or surgery
    • An enlarged prostate
    • Swelling due to a urinary tract infection
    It can also happen when poor bladder function causes a higher urine pressure that backs up into the kidney.

    Risk Factors

    Factors that may increase your chance of hydronephrosis include:
    • Defect in the urinary system that is present at birth
    • Scarring of the ureters, the tubes that carry urine from the kidneys to the bladder
    • Cancers in the pelvic area (bladder, cervix, colon, or prostate)
    • Persistent kidney or urinary tract infections
    • Blood-clotting disorders
    • Benign prostatic hyperplasia
    • Neurogenic bladder
    • Injury to structures in the urinary system, such as from surgery or trauma
    • Enlarged uterus during pregnancy


    Hydronephrosis may or may not cause any symptoms. If symptoms occur, they may include:
    • Pain in the back, waist, lower abdomen, or groin
    • Persistent pain with urination or urinary frequency from urinary tract infections
    • Increased urge to urinate or urinary incontinence
    • Incomplete urination
    • Fever
    • Nausea and vomiting
    • Unexplained itching


    You will be asked about your symptoms and medical history. A physical exam will be done. It may include a pelvic or rectal exam to feel for blockages. You may be referred to a urologist and/or nephrologist for further diagnosis and treatment.
    Your bodily fluids may be tested. This can be done with:
    • Blood tests
    • Urine tests
    Imaging tests may be done to evaluate the urinary system. This can be done with:


    A catheter may be inserted into the bladder to drain excess urine from the kidney. Some causes of hydronephrosis may also be managed with observation, such as pregnancy and kidney stones.
    Treatment options include:


    Depending on the cause, hydronephrosis may be treated with:
    • Antibiotics for infection
    • Medications for neurogenic bladder or to reduce excess uric acid excretion


    Surgery is not always needed, but it may be necessary in some cases. Procedures may include:
    • Removing the blockage or correcting a defect in the urinary system
    • Stent—A tube is placed from the kidney to the bladder to allow urine to drain past a blocked ureter.
    • Nephrostomy—A catheter is placed into the kidney. The catheter is attached to a urine collection bag.
    • Nephrectomy—Removal of part or all of the kidney (rare).


    In general, the causes of hydronephrosis cannot be prevented. Prompt treatment of conditions that cause hydronephrosis reduces the risk of complications, such as kidney failure.


    National Institute of Diabetes and Digestive and Kidney Diseases http://www.niddk.nih.gov

    National Kidney Foundation http://www.kidney.org


    Health Canada http://www.hc-sc.gc.ca

    Kidney Foundation of Canada http://www.kidney.ca


    Hydronephrosis. Cleveland Clinic website. Available at: https://my.clevelandclinic.org/health/articles/hydronephrosis. Updated March 18, 2014. Accessed April 26, 2017.

    Hydronephrosis. National Kidney Foundation website. Available at: https://www.kidney.org/atoz/content/hydronephrosis. Published 2015. Accessed April 25, 2017.

    Hydronephrosis. NHS Choices website. Available at: http://www.nhs.uk/Conditions/Hydronephrosis/Pages/Introduction.aspx. Updated June 23, 2015. Accessed April 25, 2017.

    Nephrolithiasis. EBSCO DynaMed Plus website. Available at: http://www.dynamed.com/topics/dmp~AN~T114904/Nephrolithiasis. Updated January 15, 2017. Accessed April 25, 2017.

    Obstructive uropathy. Merck Manual Professional Version website. https://www.merckmanuals.com/professional/genitourinary-disorders/obstructive-uropathy/obstructive-uropathy. Updated April 2016. Accessed April 26, 2017.

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