• Ebola Virus Disease


    Ebola virus disease is a severe infection. The infection can occur in humans and animals.


    Ebola virus disease is caused by the Ebola virus. The virus can pass from person to person through blood or other bodily fluids. When these fluids come in contact with skin or mucus membranes, the virus can pass and cause the infection. The virus can also pass through contaminated needles.
    Virus Attack on Cell
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    Risk Factors

    Travel to areas with known Ebola outbreaks increases your risk of Ebola virus disease. Almost all cases have occurred in sub-Saharan Africa.
    Your chance of Ebola virus disease also increases with:
    • Exposure to a healthcare setting that has treated a person with Ebola virus disease
    • Contact with another person who has Ebola virus disease


    Symptoms of Ebola may include:
    • Fever
    • Headache
    • Joint and muscle aches
    • Sore throat
    • Weakness
    • Diarrhea
    • Vomiting
    • Stomach pain
    • Rash
    • Red eyes
    • Hiccups
    • Internal and external bleeding


    You will be asked about your symptoms and medical history. A physical exam will be done. If you may have been exposed to the virus and have symptoms, your doctor will notify health officials. This will include the local health department and the Centers for Disease Control and Prevention.
    To confirm the presence of the virus, your doctor may order blood tests. These tests will help identify the virus itself and antibodies to the virus. Antibodies are signs that your body has identified and is fighting the virus.


    Isolation is necessary to prevent the spread of the disease.
    Treatment is focused on supporting you while your body fights the infection. Treatment may include:
    • IV fluids and electrolytes
    • Oxygen and blood pressure support
    • Treatment for any complicating infections
    • New therapies that are being tested or developed.
    Survivors may experience lingering or persistent symptoms referred to as post-Ebola syndrome. Examples of complications include:
    • Muscle and joint pain
    • Headache
    • Eye problems, including pain, discharge, redness, and blurred vision
    • Cough
    • Chest pain
    • Loss of appetite
    • Skin rash
    • Gastrointestinal problems, such as abdominal pain, nausea, vomiting, hiccups, or diarrhea
    • Left-sided weakness associated with facial nerve palsy


    To help reduce your chance of getting Ebola virus disease:
    • Avoid traveling to an area that is experiencing an outbreak.
    • If you are a healthcare worker, wear protective clothing and follow prevention protocols. This includes masks, gloves, gowns, and goggles.
    • Avoid reusing needles.
    • Avoid contact with anyone who may have been exposed to the Ebola virus.


    Centers for Disease Control and Prevention http://www.cdc.gov

    World Health Organization http://www.who.int


    Health Canada http://www.hc-sc.gc.ca

    Public Health Agency of Canada http://www.phac-aspc.gc.ca


    Ebola virus disease. Centers for Disease Control and Prevention website. Available at: http://www.cdc.gov/vhf/ebola. Updated April 14, 2016. Accessed May 31, 2016.

    Ebola virus disease. EBSCO DynaMed Plus website. Available at: http://www.dynamed.com/topics/dmp~AN~T114821/Ebola-virus-disease. Updated August 16, 2016. Accessed September 27, 2016.

    Ebola virus disease. World Health Organization (WHO) website. Available at: http://www.who.int/mediacentre/factsheets/fs103/en. Updated January 2016. Accessed May 31, 2016.

    3/28/2016 DynaMed Plus Systematic Literature Surveillance http://www.dynamed.com/topics/dmp~AN~T114821/Ebola-virus-disease: Scott JT, Sesay FR, Massaquoi TA, Idriss BR, Sahr F, Semple MG. Post-ebola syndrome, Sierra Leone. Emerg Infect Dis. 2016;22(4):641-646.

    Revision Information

    • Reviewer: David Horn, MD
    • Review Date: 05/2016
    • Update Date: 05/31/2016
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