• Symptoms of End-stage Renal Disease (ESRD)

    The Kidney and Its Main Blood Vessels
    Copyright © Nucleus Medical Media, Inc.
    As kidney failure progresses, some of the following symptoms may develop:
    • Loss of appetite
    • Nausea and vomiting
    • Fatigue
    • Weight loss
    • Itchy skin
    • Confusion
    • Trouble concentrating
    • Swelling throughout the body
    • Low urine output
    • Generalized weakness
    • Multiple bruises
    • Numbness and tingling in the extremities
    • Irritability
    • Decreased desire for sexual activity
    • Menstrual irregularities
    • Constipation
    • Diarrhea
    • Muscle cramps and twitches
    • Shortness of breath
    • Chest pain
    • Weak, brittle bones
    • Yellowish-brownish skin tone
    • Headache
    • Frequent hiccups
    If kidney failure is untreated, the waste products and fluid that build up can result in:
    • Coma
    • Seizures
    • Death


    Chronic kidney disease (CKD) in adults. EBSCO DynaMed Plus website. Available at: http://www.dynamed.com/topics/dmp~AN~T115336/Chronic-kidney-disease-CKD-in-adults. Updated August 23, 2016. Accessed October 4, 2016.

    What I need to know about kidney failure and how it's treated. National Institute of Diabetes and Digestive and Kidney Diseases website. Available at: http://www.niddk.nih.gov/health-information/health-topics/kidney-disease/kidney-failure-choosing-a-treatment-thats-right-for-you/Pages/ez.aspx. Updated September 2013. Accessed November 17, 2016.

    Yu HT. Progression of chronic renal failure. Arch Int Med. 2003;163(12):1417-1429.

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