• Hypokalemia


    Potassium is a mineral that is needed to help the heart, kidneys, and other organs function. Hypokalemia is lower than normal levels of potassium in your blood.
    All cells within the body need potassium. It works to regulate water and mineral balance throughout the body. Low levels can cause muscle and nerve problems throughout the body. It can also cause an irregular heart rate.


    Potassium enters the body through food and digestion. It passes out of the blood through the kidneys. Hypokalemia occurs when there is not enough potassium being absorbed into the body, too much potassium is removed by the kidneys, or potassium moves from the blood into the cells.

    Risk Factors

    Factors that may increase with potassium excretion through the kidneys include:
    • Certain medications such as diuretics or beta-2-adrenergic agonists, such as albuterol
    • Kidney disease or failure—too much potassium excreted
    • Significant elevation of glucose from poorly controlled diabetes
    Factors that may shift potassium into cells:
    • Treatment of elevated glucose and ketoacidosis from poorly controlled diabetes
    • Rapid refeeding after starvation
    • Delirium tremens from severe alcohol withdrawal
    • Excess loss of potassium from diarrhea or sweating
    Kidney Damage
    Copyright © Nucleus Medical Media, Inc.
    Factors that may decrease your intake or absorption of potassium include:
    • Poor diet
    • Eating disorders
    • Excess alcohol intake
    • Vomiting or diarrhea


    Early hypokalemia may not have any symptoms. When symptoms do occur, they may include:
    • Fatigue
    • Muscle weakness
    • Constipation
    • Difficulty breathing
    • Tingling or numbness
    • Irregular heartbeat
    • Fainting


    You will be asked about your symptoms and medical history. A physical exam will be done.
    Potassium levels in your body fluids will be tested with:
    • Blood tests
    • Urine tests
    An electrocardiogram (EKG) may be done to see if the potassium is affecting your heart.


    The main goal of treatment is to increase the level of potassium in your body. Talk with your doctor about the best treatment plan for you. Options include:


    IV fluids may be given. You may also be given the following to raise the amount of potassium in your blood if it is very low:
    • Potassium
    • Magnesium—if it is also low
    Your current medications may be changed if they are the cause of your hypokalemia.
    Any underlying condition will be treated.

    Dietary Changes

    You may be advised to increase the amount of potassium in your diet. You may be referred to a dietitian to help you balance the potassium in your diet.


    To help reduce your chance of hypokalemia:
    • Eat a diet that contains enough potassium.
    • Manage conditions, such as diabetes.
    • Keep your doctor informed of the medications you are taking and any problems you have taking them correctly.


    American Association of Clinical Endocrinologists http://www.aace.com

    Family Doctor—American Academy of Family Physicians http://www.familydoctor.org


    Health Canada http://www.hc-sc.gc.ca

    The Canadian Society of Endocrinology and Metabolism http://www.endo-metab.ca


    Hypokalemia. EBSCO DynaMed Plus website. Available at: http://www.dynamed.com/topics/dmp~AN~T115951/Hypokalemia. Updated September 17, 2015. Accessed October 3, 2016.

    Hypokalaemia. Patient UK website. Available at: http://patient.info/doctor/hypokalaemia. Updated December 4, 2013. Accessed February 17, 2015.

    Hypokalemia. NORD website. Available at: https://www.rarediseases.org/rare-disease-information/rare-diseases/byID/748/viewFullReport. Updated February 2, 2008. Accessed February 17, 2015.

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